allosteric modulator造句

• A positive ago-allosteric modulator increases both efficacy and potency.
• Oxiracetam acts also as a positive allosteric modulator of the AMPA receptors.
• Methylphenylpiracetam is a positive allosteric modulator of the sigma-1 receptor.
• RO4491533 acts as a negative allosteric modulator of mGluR 2 and mGluR 3.
• Alcohol acts as a positive allosteric modulator and therefore amplifies the transmitter s inhibitory effects.
• Levamlodipine is an allosteric modulator and acts on the L-type of calcium channels.
• A heterotropic allosteric modulator is a regulatory molecule that is not the enzyme's substrate.
• It was further shown to act as an allosteric modulator of the sigma-1 receptor.
• It acts as a positive allosteric modulator of the benzodiazepine site of the GABA A receptor.
• It acts as a negative allosteric modulator of the intermediate in this two-step transformation.
• It is an ? 1 receptor, a negative allosteric modulator of the nicotinic acetylcholine receptor,
• Evans blue is pharmacologically active, acting as a negative allosteric modulator of the vesicular glutamate transporters.
• In 1993, it was discovered that cyclothiazide is a positive allosteric modulator of the neuronal death.
• At low or moderate doses, alcohol acts primarily as a positive allosteric modulator of GABA A.
• "' SoRI-9804 "'is a positive allosteric modulator of dopamine transporters.
• Lanthanum acts at the same modulatory site on the GABA receptor as zinc, a known negative allosteric modulator.
• SX-3228 is a subtype-selective GABA A positive allosteric modulator acting primarily at the ?1 subtype.
• Thymol has been shown to act as a positive allosteric modulator of GABA A " in vitro ".
• Fluoxetine increases the concentration of circulating allopregnanolone, a potent GABA A receptor positive allosteric modulator, in the brain.
• The agonist, antagonist and allosteric modulator drugs of mGluR3 can now be explored as new treatments for mental illness.